Lantern Pharma Completes LP-184 Phase 1a Enrollment, Advances AI-Driven Oncology Pipeline

Lantern Pharma Inc. has completed enrollment in its LP-184 Phase 1a trial, enrolling 65 patients and establishing both the maximum tolerated dose and recommended Phase 2 dose for the synthetic acylfulvene drug candidate. This milestone enables the company to proceed with planned Phase 1b/2 trials targeting recurrent triple negative breast cancer and other difficult-to-treat malignancies, representing significant progress in addressing cancers with substantial market potential.

The clinical-stage biotechnology company reported early patient responses across multiple oncology drug candidates, including LP-184, LP-284, and LP-300 trials, demonstrating clinical activity in challenging cancer types. This multi-program advancement reflects Lantern Pharma's strategic approach to developing targeted cancer therapies while maintaining operational efficiency and disciplined cost control.

Lantern Pharma has significantly expanded its intellectual property portfolio with a new European patent allowance for LP-284 and the publication of a blood-brain barrier prediction patent. The company's RADR artificial intelligence platform has been enhanced with the public launch of predictBBB.ai and the introduction of a new drug combination module, strengthening its drug development capabilities and positioning the company at the forefront of AI-driven oncology research.

Financially, Lantern ended the second quarter with $15.9 million in cash, with management expecting the runway to extend into mid-2026. Research and development expenses declined year-over-year, reflecting the company's disciplined approach to cost control while advancing multiple clinical trials. The company continues to leverage artificial intelligence and machine learning to redefine oncology drug development, supported by funding stability as detailed in company statements available at https://ibn.fm/xEtvR.

The combination of clinical progress, intellectual property expansion, and financial discipline demonstrates Lantern Pharma's comprehensive strategy for developing innovative cancer treatments. These advancements position the company to address high-value oncology markets with potentially transformative therapies, leveraging both traditional drug development approaches and cutting-edge AI technologies to improve outcomes for patients with difficult-to-treat cancers.